The Woman To Woman star spoke out on Twitter against the "self righteous" track, which has divided opinion since its surprise release on Sunday night.
"Can't stand when people all self righteous when it's convenient it makes them look good. Lmao! But can still talk s**t when convenient 2 FOH (sic)" she wrote.
Unsurprisingly, the 'Crazy In Love' star's army of fans have not taken too kindly to Keisha's comments, to which she responded: "I done kept it real from the start! #RespectTHAT.
"First "Women need to Stick together" now bitches better Bow. Smh. But it's all G! Chicks stay shooting the s**t. But when I speak my mind its a prob. #Well #StayMad."
'Self righteous'? Beyonce debuts her new documentary (WENN)
Firing back at one critical response, she added: "How am i hating? no Mamm or sir. whatever u may be. No H8 RT @GothamsKnight_: damn @KeyshiaCole hating on everybody."
She had previously criticised Beyonce's Destiny's Child bandmate Michelle Williams following her Super Bowl appearance.
One person who's defended Bey from her critics is Ne-Yo, who insisted following her Life Is But A Dream documentary that she is not as much of a diva as some of her music might have you believe.
“She's the exact same person she was the first time I met her,” he told Capital FM.
“She's super dooper down to earth. A lot of people feel like Beyonce would get on TV and put on a front and try to play it up for the camera – she doesn't!
“She's really and truly and genuinely, what you see is what you get. People need to lay off with all the stupidness that they're talking about. Who she is, is who you see.”
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